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    Mia,* a 41-year-old CPA, started seeing me for help with her depressive symptoms.

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  • A combination of work stress at a new firm plus worry about her mom's health challenges contributed to a recurrence of depression that had first occurred when she was in her 20s.

    She was given an antidepressant at the time but had significant nausea early on and stopped after three weeks.

    "I don't think antidepressants work for me," she said.

    This time around, though, the depression was debilitating enough that she started to miss important work deadlines. Given her overall impaired functioning, I made the recommendation that we add antidepressants to our therapy work.

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    However, she had concerns: "They didn't help me before and I'm worried they won't do much for me this time, either."

    According to a U.S. National Center for Health Statistics survey, antidepressants are the most common drugs used by 18- to 44-year-olds, and the third most common for all adults.

    Yet frequently, patients don't have the full picture of how they work.

    Informed is always better. Here are seven key points people should

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